Successfully supplying the various life sciences industries since 1982, Aquabona has one of the largest installed bases in
applications for the Pharmaceutical and Personal Care industry
Our systems are efficient, offer consistent performance and have been specially designed to meet application standards in
WFI (Water-For-Injection) and USP (United States Pharmacopoeia). Validated systems, with supply of validated UV lamps and UV sensors with certificates
traceability by NIST, as well as amalgam technology that has been subjected to a bioassay process. All systems meet the requirements
of cGMP and FDA and the sanitary connections conform to DIN and USDA 3A standards.
Most common applications
This is the most common application of UV in water treatment. A UV unit can significantly reduce microbe counts by destroying the
least 99.9% of the bacteria present in the influent flow.
The pharmaceutical water line could have several points where UV equipment would be installed. Some typical installation locations would be downstream
of the carbon filter and/or directly upstream of the RO plant. It is also recommended to disinfect the process distribution loop -to the discharge,
the return and even both- as well as the pre-storage tank.
OptiVenn product line
SwiftBeverage product line (bioassay validation)
USP 31 regulations require a maximum limit of 500ppb for TOC for both Purified Water (PW) and Water for Injection (WFI).
TOC reduction is achieved through a powerful UV system at 185nm wavelength, appropriately designed and sized
for the fulfillment of this application.
Avant product line
Ozone is commonly used in water line pretreatment, as well as for the sanitization process and recirculation circuits. Nevertheless,
Before the point of use, residual dissolved ozone has to be destroyed to ensure that the process water is not compromised.
UV technology is the preferred method for this application mainly because it is a non-chemical and fast-reacting process. After taking
of the appropriate design parameters, the choice of the appropriate UV unit guarantees the destruction of ozone to non-detectable values, ensuring the integrity
of the process and the product. For the destruction of 1.0 ppm of residual ozone a UV dose of 90 mJ/cm2 is recommended.
OptiVenn line product
While adding chlorine to the water system can control bacteria levels, it should not be forgotten that it has undesirable effects on degradation.
of filtration and RO membranes.
In addition, popular methods of removing chlorine and chloramines, such as carbon beds or chemical injection, have proven to be problematic.
Sodium metabisulfite involves the elimination of one chemical substance through the use of another, generating food for microorganisms, while
Coal beds can be inefficient, vulnerable to preferential channel formation, providing a breeding ground for microorganisms.
The application of UV radiation technology for the destruction of chlorine and chloramines pre-filtration membrane and RO for water conditioning is being
establishing itself as the most sustainable alternative.
Meet strict pharmaceutical water regulations by applying Pall filtration, purification and separation technologies.
Solutions to comply with strict pharmaceutical water treatment regulations.
Pharmaceutical manufacturers face strict water purity regulations. These regulations regulate the quality of purified water, water
highly purified and water for injection. These waters are used in a wide variety of applications, such as bulk primary processing, preparation
of media, rinsing of equipment and containers, final formulations, etc.
Inlet water used in the manufacturing of pharmaceutical products must also meet specific criteria. This water can be used in
early stages of synthesis or in cleaning, and as feed water for high purity water treatment systems. Normally, this water should
meet drinking water standards and often has additional limits specified for hardness, silica, and total bacteria count.
Typical Water Line Scheme in a Pharmaceutical Plant