Successfully supplying the various life sciences industries since 1982, Aquabona has one of the largest installed bases in
applications for the Pharmaceutical and Personal Care industry
Our systems are efficient, offer consistent performance and have been specially designed to meet application standards in
WFI (Water-For-Injection) and USP (United States Pharmacopoeia). Validated systems, with supply of validated UV lamps and UV sensors with traceability
certificates, as well as amalgam technology that has undergone a bioassay process. All systems have sanitary connections
according to DIN and USDA 3A standards.
Most common applications
Desinfection
This is the most common application of UV in water treatment. A UV unit can significantly reduce microbe counts by destroying the
least 99.9% of the bacteria present in the influent flow.
The pharmaceutical water line could have several points where UV equipment would be installed. Some typical installation locations would be downstream
of the carbon filter and/or directly upstream of the RO plant. It is also recommended to disinfect the process distribution loop -to the discharge,
the return and even both- as well as the pre-storage tank.
OCD reduction
USP 31 regulations require a maximum limit of 500ppb for TOC for both Purified Water (PW) and Water for Injection (WFI).
TOC reduction is achieved through a powerful UV system at
185nm wavelength, appropriately designed and sized
for the fulfillment of this application.
Ozone destruction
Ozone is commonly used in water line pretreatment, as well as for the sanitization process and recirculation circuits. Nevertheless,
Before the point of use, residual dissolved ozone has to be destroyed to ensure that the process water is not compromised.
UV technology is the preferred method for this application mainly because it is a non-chemical and fast-reacting process. After taking
of the appropriate design parameters, the choice of the appropriate UV unit guarantees the destruction of ozone to non-detectable values, ensuring the integrity
of the process and the product. For the destruction of 1.0 ppm of residual ozone a UV dose of 90 mJ/cm2 is recommended.
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Chlorine/Chloramine Destruction
While adding chlorine to the water system can control bacteria levels, it should not be forgotten that it has undesirable effects on degradation.
of filtration and RO membranes.
In addition, popular methods of removing chlorine and chloramines, such as carbon beds or chemical injection, have proven to be problematic.
Sodium metabisulfite involves the elimination of one chemical substance through the use of another, generating food for microorganisms, while
Coal beds can be inefficient, vulnerable to preferential channel formation, providing a breeding ground for microorganisms.
The application of UV radiation technology for the destruction of chlorine and chloramines pre-filtration membrane and RO for water conditioning is being
establishing itself as the most sustainable alternative.
Mobile Plants (for rent)
AquaMobile© mobile plants from
Proxa, on a
rental basis, to cover water needs in emergency
or long-term situations in Industrial applications.
✓ Emergency situations
✓ Failures in existing equipment
✓ Seasonal water demand surges exceeding system capacity
✓ Planned interruptions due to maintenance, upgrading or replacement of the existing system
Containerized systems are quickly and easily installed to begin producing high quality water within four hours of arrival on site.
AquaMobile© is an ideal solution to complement or replace your existing water treatment system, whether to meet permanent or
temporary needs.
Wide range of technologies:
• Lamellar settling
• Sand bed / drum filtration
• Desalination / RO
• Ion exchange
• Evaporation and crystallization
• MF/ UF
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Typical Water Line Scheme in a Pharmaceutical Plant
